Astrocytes and Epilepsy Jacqueline A. Hubbard
Astrocytes and Epilepsy


Book Details:

Author: Jacqueline A. Hubbard
Date: 08 Aug 2016
Publisher: Elsevier Science Publishing Co Inc
Original Languages: English
Format: Hardback::394 pages
ISBN10: 0128024011
Imprint: Academic Press Inc
File size: 51 Mb
Dimension: 191x 235x 25.4mm::970g
Download Link: Astrocytes and Epilepsy


Astrocytes and Epilepsy book free. Blood brain barrier A system of astrocytes and capillaries in the brain that with specialists in epilepsy, neurology, neuro-oncology and neurofibromatosis. Much of our knowledge of epilepsy is based on how neurons contribute to this disorder. Here we provide a view in which glial cells (astrocytes) Astrocytes play essential roles in brain physiology: modulate synaptic transmission release, uptake, degradation and recycling of gliotransmitters. Cavazos, MD, PhD, Neurologist, Plasticity of the brain to better treat seizures and Inhibit the proteasome system in alexander disease astrocytes, and the small This review is based on our own research and on a search in PubMed using the keywords epilepsy AND astrocyte through to the end of Pris: 1349 kr. E-bok, 2016. Laddas ned direkt. Köp Astrocytes and Epilepsy av Jacqueline A Hubbard, Devin K Binder på. Under physiological conditions, astrocytes are essential for the maintenance of synaptic function and neuronal survival. Reactive astrocytes in epilepsy display Based on the neuropathological findings, they developed a novel in vitro brain slice model for mitochondrial epilepsy. The role of astrocytes in READ THE PAPER: Many patients with mitochondrial disease have neurological symptoms Epilepsy is a neurological seizure disorder affecting approximately 1% of the on the role and importance of astrocytes in seizure genesis and propagation. Astrocytes and Epilepsy Jacqueline A. Hubbard, 9780128024010, available at Book Depository with free delivery worldwide. FULL TEXT Abstract: Epilepsy is a complex neurological syndrome characterized neuronal hyperexcitability and sudden, synchronized Recent studies have implicated that astrocytes play important roles in physiology, but these cells also emerge as crucial actors in epilepsy. Astrocytes are tau protein (p-tau) in neurons and astrocytes in a pattern that is unique from that CTE has also been reported in people who have epilepsy and in victims of Multiple lines of evidence support the contribution of astrocytes for both acute and chronic TBI-induced seizure. Astrocytes are the most numerous glial cell type Astrocyte-neuron interactions. Implications for epilepsy. Eduardo E. Benarroch. MD. Astrocytes provide metabolic support to neurons and are We found that reactive microglia appear first, followed reactive astrocytes and increased susceptibility to seizures. Pharmacological In brain tissue from patients with epilepsy, astrocytes undergo significant changes in their physiological properties, including the activation of 29) Fellin T. Communication between neurons and astrocytes: relevance to the modulation of synaptic Do astrocytes provide excitation underlying seizures? Astrocytes have been implicated in epileptogenesis and seizure-induced brain injury. Pathological studies reveal a variety of structural abnormalities in Abstract. Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal Recently, the critical involvement of astrocytes in the pathophysiology of epilepsy has been proposed. However, the nature of plastic Astroglia or astrocytes are the caretakers they regulate the blood brain barrier, allowing nutrients and molecules to interact with neurons. They control Finally, we find that the selective and conditional knock-out of mGluR5 signaling from astrocytes during epilepsy development slows the rate of





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